Al-Sayyida Nafisa Mosque or Mashhad al-Sayyida Nafisa is a mosque in al-Sayyida Nafisa district (or ), a section of the larger historic necropolis called al-Qarafa (or City of the Dead) in Cairo, Egypt. It is built to commemorate Sayyida Nafisa, an acclaimed Islamic scholar and a member of Bayt (household) of the Islamic prophet Muhammad. The mosque has Sayyida Nafisa's mausoleum inside. Along with the necropolis around it, it is listed as part of the UNESCO World Heritage Site of Historic Cairo.