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Zolbetuximab (development code IMAB362) is an experimental monoclonal antibody against isoform 2 of Claudin-18. It is under investigation for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors. IMAB362 was developed by Ganymed Pharmaceuticals AG. The drug is in phase III clinical trials as of November 2021. Preliminary results from the phase II 'FAST' trial in June 2016 suggest it is helpful for advanced gastric cancer.

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rdf:type
rdfs:label
  • Zolbetuximab (en)
rdfs:comment
  • Zolbetuximab (development code IMAB362) is an experimental monoclonal antibody against isoform 2 of Claudin-18. It is under investigation for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors. IMAB362 was developed by Ganymed Pharmaceuticals AG. The drug is in phase III clinical trials as of November 2021. Preliminary results from the phase II 'FAST' trial in June 2016 suggest it is helpful for advanced gastric cancer. (en)
dcterms:subject
Wikipage page ID
Wikipage revision ID
Link from a Wikipage to another Wikipage
sameAs
dbp:wikiPageUsesTemplate
ATC prefix
  • none (en)
CAS number
ChemSpiderID
  • none (en)
legal status
  • Investigational (en)
source
  • xi (en)
synonyms
  • IMAB362; Claudiximab (en)
target
  • CLDN18.2 (en)
type
  • mab (en)
UNII
  • TF5MPQ8WGY (en)
Verifiedfields
  • changed (en)
verifiedrevid
has abstract
  • Zolbetuximab (development code IMAB362) is an experimental monoclonal antibody against isoform 2 of Claudin-18. It is under investigation for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors. IMAB362 was developed by Ganymed Pharmaceuticals AG. The drug is in phase III clinical trials as of November 2021. Preliminary results from the phase II 'FAST' trial in June 2016 suggest it is helpful for advanced gastric cancer. (en)
mab type
  • mab (en)
prov:wasDerivedFrom
page length (characters) of wiki page
CAS number
  • 1496553-00-4
FDA UNII code
  • TF5MPQ8WGY
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