About: Zhijian Chen

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Zhijian "James" Chen (Chinese: 陈志坚; pinyin: Chén Zhìjiān; born 1966) is a Chinese-American biochemist and Professor in the Department of Molecular Biology at University of Texas Southwestern Medical Center. He is best known for his discovery of mechanisms by which nucleic acids trigger innate and autoimmune responses from the interior of a cell, work for which he received the 2019 Breakthrough Prize in Life Sciences.

Attributes	Values
rdf:type	Thing foaf:Person person dul:NaturalPerson Eukaryote Person Human Animal animal eukaryote scientist species schema:Person Scientist
rdfs:label	Zhijian Chen (de) Чэнь Чжицзянь (ru) Zhijian Chen (en) Чжицзянь Чень (uk) 陈志坚 (1966年) (zh)
rdfs:comment	Zhijian "James" Chen (Chinese: 陈志坚; pinyin: Chén Zhìjiān; born 1966) is a Chinese-American biochemist and Professor in the Department of Molecular Biology at University of Texas Southwestern Medical Center. He is best known for his discovery of mechanisms by which nucleic acids trigger innate and autoimmune responses from the interior of a cell, work for which he received the 2019 Breakthrough Prize in Life Sciences. (en) 陈志坚（1966年1月－），泉州安溪人，美国生物化学家，得克萨斯大学西南医学中心分子生物学系教授。美国国家科学院院士。他最有名的工作是使用生物化学方法发现未锚泛素链在激酶活动中的角色，线粒体和普里昂式的在炎症和免疫信号中的参与。陈志坚目前担任生物医学科学乔治·麦格雷戈特聘讲座，且是霍华德·休斯医学研究所的研究员。 (zh) Чжицзянь Чень (спрощ.: 陈志坚; піньїнь: Chén Zhìjiān; нар. 1966) — китайсько-американський біохімік та імунолог. Доктор філософії (1991), професор ., дослідник (з 2005) Ще на початку своєї кар'єри відкрив роль убіквітину. В 2012 році відкрив . Чень народився в селі Нанду (南斗), повіт , Фуцзянь, Китай. В 1985 році закінчив з біології та в 1991 році з біохімії — в останньому здобув ступінь доктора філософії. Був постдоком у , . (uk) Zhijian „James“ Chen (* Januar 1966 in einem Dorf in Anxi (Quanzhou)) ist ein chinesisch-US-amerikanischer Biochemiker und Hochschullehrer am . Chen studierte an der Fujian Normal University mit dem Bachelor-Abschluss in Biologie 1985 und an der State University of New York at Buffalo, an der er 1991 in Biochemie promovierte. Als Post-Doktorand war er am Salk-Institut. Er forschte für die Firma Baxter Healthcare in Irvine (Kalifornien) und die Biotechnikfirma ProScript in Cambridge (Massachusetts) (die an der Therapie mit dem Chemotherapeutikum gegen Krebs Bortezomib (Velcade) arbeitete). Dort begann auch seine Forschung über Ubiquitin (mit Tom Maniatis). Ab 1997 setzte er seine Forschung am Southwestern Medical Center der University of Texas fort. Er ist dort George L. MacGregor Professor (de) Чэнь Чжицзя́нь (кит. упр. 陈志坚, пиньинь Chén Zhìjiān; род. 1966) — китайско-американский биохимик и иммунолог.Доктор философии (1991), профессор , исследователь Медицинского института Говарда Хьюза (с 2005), член Национальной академии наук США (2014). Ещё в начале своей карьеры открыл роль убиквитина.В 2012 году открыл . С 1997 года трудится в , где ныне профессор.Он стал там первым поступившим в штат новосозданной и возглавленной Эриком Олсоном кафедры молекулярной биологии.Работает под началом Брюса Бётлера, нобелевского лауреата 2011 года. Входит в Консультативный совет Oskar Fischer Prize. (ru)
foaf:name	Zhijian "James" Chen (en)
name	Zhijian "James" Chen (en)
birth place	Fujian Anxi County
birth place	Anxi County, Fujian, China (en)
dcterms:subject	University of Texas Southwestern Medical Center faculty Living people Chemists from Fujian Educators from Fujian Hokkien scientists People from Quanzhou 1966 births American biochemists Members of the United States National Academy of Sciences University at Buffalo alumni American people of Chinese descent Chinese emigrants to the United States Biologists from Fujian Howard Hughes Medical Investigators Chinese biochemists
Wikipage page ID	35484955 (xsd:integer)
Wikipage revision ID	1028630719 (xsd:integer)
Link from a Wikipage to another Wikipage	Cambridge, Massachusetts Biochemistry Breakthrough Prize in Life Sciences University of Texas Southwestern Medical Center faculty Howard Hughes Medical Institute Cyclic GMP-AMP synthase University of Texas Southwestern Medical Center Science Daily Living people Salk Institute for Biological Studies Fujian Fujian Normal University NF-κB Anxi County Chemists from Fujian Educators from Fujian Hokkien scientists People from Quanzhou Chinese-American 1966 births American biochemists Members of the United States National Academy of Sciences University at Buffalo alumni Burroughs Wellcome Fund American people of Chinese descent Chinese emigrants to the United States Tom Maniatis Biologists from Fujian Adrian R. Krainer dbr:Cyclic_guanosine_monophosphate–adenosine_monophosphate Dallas, Texas Angelika Amon Kinase Harvard University Hepatitis C Irvine, California Assays Howard Hughes Medical Investigators C. Frank Bennett Influenza Nanping National Academy of Sciences National Institutes of Health Chinese biochemists RNA viruses Xiaowei Zhuang Ubiquitin Immune response Lurie Prize in Biomedical Sciences NAS Award in Molecular Biology Velcade Mitochondrial antiviral-signaling protein University at Buffalo, The State University of New York Baxter Healthcare

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