Yvonne L. Rayford Brown (September 8, 1952 – April 23, 2012) was an American politician and member of the Republican Party from the state of Mississippi. She was elected as Mayor of Tchula, serving two terms from 2001 to 2009. This small town is in Holmes County on the eastern edge of the Mississippi Delta. She was also the Republican nominee for Mississippi's 2nd congressional district in the United States House of Representatives in the 2006 mid-term elections.