Widnes South railway station was located in the town of Widnes in Cheshire, England on the east side of Victoria Road. It was built by the London and North Western Railway and situated on their Widnes Deviation Line, opening to passengers and goods in March 1870. This route was constructed by the LNWR to improve traffic flow on the busy Ditton Junction to Warrington Bank Quay Low Level and Manchester (the former Garston and Warrington Railway, later renamed as the St Helens Railway). It replaced an earlier station on the G&WR line located slightly further south and also had a connection to the St Helens and Runcorn Gap Railway, providing access towards the north.