War Chamber (2021) was a professional wrestling supercard event produced by Major League Wrestling (MLW), which took place on November 6, 2021, at the 2300 Arena in Philadelphia, Pennsylvania. The event was a television taping for MLW Fusion: Alpha on MLW's YouTube channel and beIN Sports USA, with the main event streaming as a special episode that aired on November 17, 2021. It was the second event under the War Chamber chronology, and featured the finals of the 2021 Opera Cup.