About: Vascular remodelling in the embryo     Goto   Sponge   NotDistinct   Permalink

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Vascular remodelling is a process which begins usually at day 22, and continues to around the tenth week of human embryogenesis, when, on day 22, an immature heart begins contracting, pushing fluid through the early vasculature. This first passage of fluid initiates a signal cascade and cell movement based on physical cues including shear stress and circumferential stress, which is necessary for the remodelling of the vascular network, arterial-venous identity, angiogenesis, and the regulation of genes through mechanotransduction. This embryonic process is necessary for the future stability of the mature vascular network.

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  • Vascular remodelling in the embryo
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  • Vascular remodelling is a process which begins usually at day 22, and continues to around the tenth week of human embryogenesis, when, on day 22, an immature heart begins contracting, pushing fluid through the early vasculature. This first passage of fluid initiates a signal cascade and cell movement based on physical cues including shear stress and circumferential stress, which is necessary for the remodelling of the vascular network, arterial-venous identity, angiogenesis, and the regulation of genes through mechanotransduction. This embryonic process is necessary for the future stability of the mature vascular network.
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