U.S. Route 6 (US 6) is a part of the United States Numbered Highway System that runs from Bishop, California to Provincetown, Massachusetts. US 6 is the second longest federal highway in the United States, second only to U.S. Route 20. In Ohio, the road runs west-east from the Indiana state line near Edgerton to the Pennsylvania state line near Andover. The 248.002 miles (399.121 km) that lie in Ohio are maintained by the Ohio Department of Transportation (ODOT). US 6 serves the major cities of Sandusky, Lorain, and Cleveland. The highway is also called the Grand Army of the Republic Highway to honor the Union forces of the American Civil War. The alternate name was designated in 1953.