Toowoomba South State School is a heritage-listed former school at 158 James Street, South Toowoomba, Toowoomba, Toowoomba Region, Queensland, Australia. It was designed by Department of Public Works (Queensland). It was added to the Queensland Heritage Register on 2 December 2013. Toowoomba South is one of the oldest primary schools in Queensland. It is the oldest State School in Toowoomba (although nearby Drayton State School is older). It was first opened in 1865, as school number 112. Initially the school was co-educational. It was closed in 2013.