Theta Upsilon Omega (ΘΥΩ), was a national collegiate fraternity in the United States. Representatives of several local fraternities at a December 1, 1923 meeting of locals, organized by the National Interfraternity Conference, determined to form a new national through amalgamation, resulting in the creation of Theta Upsilon Omega on May 2, 1924. On April 23, 1938, Theta Upsilon Omega merged with Sigma Phi Epsilon.