Theophilus Herman Kofi Opoku (1842 – 7 July 1913) was a native Akan linguist, translator, philologist, educator and missionary who became the first indigenous African to be ordained a pastor on Gold Coast soil by the Basel Mission in 1872. Opoku worked closely with the German missionary and philologist Johann Gottlieb Christaller as well as fellow native Akan linguists, David Asante, Jonathan Palmer Bekoe, and Paul Staudt Keteku in the translation of the Bible into the Twi language.