The Last Sweet Days of Isaac is an American Off-Broadway rock musical by Gretchen Cryer and , which premiered in 1970. It starred Austin Pendleton and , and later Alice Playten. It received positive reviews, and won three Obies, a Drama Desk Award, and an Outer Critics Circle Award. It opened at the Eastside Playhouse on January 26, 1970, and closed May 2, 1971.