Steven G. Clarke, (born November 19, 1949) an American biochemist, is a director of the UCLA Molecular Biology Institute, a professor of chemistry and biochemistry at UCLA biochemistry department. Clarke heads a laboratory at UCLA's department of chemistry and biochemistry. Clarke is famous for his work on molecular damage and discoveries of novel molecular repair mechanisms. Clarke has been on the faculty of the UCLA Department of Chemistry and Biochemistry since 1978. He is currently a Professor of Biochemistry and Director of the UCLA Molecular Biology Institute.