St. Mary Catholic Central High School, known colloquially as SMCC, is a Catholic, co-educational, parochial, secondary school located at 108 West Elm Avenue in Monroe, Michigan. SMCC is sponsored by the Catholic parishes of the Vicariate of Monroe under the auspices of the Roman Catholic Archdiocese of Detroit. The school itself is listed as a contributing property within the St. Mary's Church Complex Historic District.