The men's ISSF 50 meter pistol was a shooting sports event held as part of the Shooting at the 1960 Summer Olympics programme. It was the tenth appearance of the event. The competition was held on 5 and 6 September 1960 at the Umberto I Shooting Range in Rome. 67 shooters from 40 nations competed. Nations had been limited to two shooters each since the 1952 Games. The event was won by Aleksey Gushchin of the Soviet Union, as the Soviet team finished 1–2 with Makhmud Umarov repeating as silver medalist (the third man to earn multiple medals in the event). Yoshihisa Yoshikawa (who would become the fourth multi-medalist four years later) of Japan took bronze.