A serodiscordant relationship, also known as mixed-status, is one where one partner is infected by HIV and the other is not. This contrasts with seroconcordant relationships, in which both partners are of the same HIV status. Serodiscordancy contributes to the spread of HIV/AIDS, particularly in Sub-Saharan nations such as Lesotho. Research involving serodiscordant couples has offered insights into how the virus is passed and how individuals who are HIV positive may be able to reduce the risk of passing the virus to their partner.
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| - Serodiskordanz (de)
- Serodiscordant (en)
- Sorodiferente (pt)
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| - Unter einer serodiskordanten Beziehung versteht man eine sexuelle Beziehung, bei der ein Partner mit HIV infiziert ist und der andere nicht. Dies steht im Gegensatz zu serokonkordanten Beziehungen, bei denen beide Partner den gleichen HIV-Status haben, also beide Partner entweder HIV-positiv oder HIV-negativ sind. Serodiskordanz trägt zur Verbreitung von HIV / AIDS bei, insbesondere in den Ländern südlich der Sahara wie Lesotho. Die Serodiskordanz ergibt sich aus einem ungleichen Serostatus beispielsweise zwischen zwei Partnern oder Zwillingen, von denen einer HIV-positiv, der andere HIV-negativ ist. (de)
- A serodiscordant relationship, also known as mixed-status, is one where one partner is infected by HIV and the other is not. This contrasts with seroconcordant relationships, in which both partners are of the same HIV status. Serodiscordancy contributes to the spread of HIV/AIDS, particularly in Sub-Saharan nations such as Lesotho. Research involving serodiscordant couples has offered insights into how the virus is passed and how individuals who are HIV positive may be able to reduce the risk of passing the virus to their partner. (en)
- Uma relação sorodiscordante ou sorodiferente, também conhecida como estado misto, é aquela em que um dos parceiros está infectado pelo HIV e o outro não. Isso contrasta com as relações soroconcordantes, nas quais ambos os parceiros têm a mesma sorologia ou o mesmo sorotipo para o HIV. A sorodiscordância ou sorodiferença contribui para a disseminação do HIV/AIDS, particularmente nas nações subsaarianas como o Lesoto. Pesquisas envolvendo casais sorodiferentes ofereceram percepções sobre como o vírus é transmitido e como os indivíduos HIV positivos podem reduzir (pt)
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| - Unter einer serodiskordanten Beziehung versteht man eine sexuelle Beziehung, bei der ein Partner mit HIV infiziert ist und der andere nicht. Dies steht im Gegensatz zu serokonkordanten Beziehungen, bei denen beide Partner den gleichen HIV-Status haben, also beide Partner entweder HIV-positiv oder HIV-negativ sind. Serodiskordanz trägt zur Verbreitung von HIV / AIDS bei, insbesondere in den Ländern südlich der Sahara wie Lesotho. Die Serodiskordanz ergibt sich aus einem ungleichen Serostatus beispielsweise zwischen zwei Partnern oder Zwillingen, von denen einer HIV-positiv, der andere HIV-negativ ist. Eine tägliche Präexpositionsprophylaxe (PrEP) mit TDF (Tenofovir-Disoproxil-Fumarat) oder TDF-FTC (mit Emtricitabin) reduziert das Risiko einer HIV-Übertragung bei serodiskordanten Paaren. Bei Paaren, bei denen der Mann mit HIV infiziert ist, die Frau jedoch nicht, hat sich der Einsatz von Sperma-Präparationstechniken in Verbindung mit Inseminationen oder In-vitro-Fertilisation (IVF) mit intrazytoplasmatischer Spermieninjektion (ICSI) als sehr wirksam erwiesen, um die Serokonversion von nicht infizierten Frauen und deren Föten zu vermeiden. Das Sperm washing kann verwendet werden, um das Risiko einer HIV-Übertragung bei HIV-positiven Männern zu senken, da die Infektion eher durch die Samenflüssigkeit als durch die Spermien selbst erfolgt. Eine italienische Studie aus dem Jahr 2005 von 567 behandelten serodiskordanten Paaren ergab keine horizontale (für die Frau) oder vertikale (für das Kind) HIV-Serokonversion. (de)
- A serodiscordant relationship, also known as mixed-status, is one where one partner is infected by HIV and the other is not. This contrasts with seroconcordant relationships, in which both partners are of the same HIV status. Serodiscordancy contributes to the spread of HIV/AIDS, particularly in Sub-Saharan nations such as Lesotho. Serodiscordant couples face numerous issues not faced by seroconcordant couples, including decisions as to what level of sexual activity is comfortable for them, knowing that practicing safer sex reduces but does not eliminate the risk of transmission to the HIV-negative partner. There are also potential psychological issues arising out of taking care of a sick partner, and survivor guilt. Financial strains may also be more accentuated as one partner becomes ill and potentially less able or unable to work. Research involving serodiscordant couples has offered insights into how the virus is passed and how individuals who are HIV positive may be able to reduce the risk of passing the virus to their partner. Experts predict that there are thousands of serodiscordant couples in the US who wish to have children, and researchers report a growing stream of calls from these couples wanting reproductive help. The Special Program of Assisted Reproduction was developed in 1996 to help serodiscordant couples conceive safely, however, it is solely designed to help couples where the male partner is infected. WHO 2013 guidelines for starting assisted reproduction technology now consider all serodiscordant couples for treatment. (en)
- Uma relação sorodiscordante ou sorodiferente, também conhecida como estado misto, é aquela em que um dos parceiros está infectado pelo HIV e o outro não. Isso contrasta com as relações soroconcordantes, nas quais ambos os parceiros têm a mesma sorologia ou o mesmo sorotipo para o HIV. A sorodiscordância ou sorodiferença contribui para a disseminação do HIV/AIDS, particularmente nas nações subsaarianas como o Lesoto. Os casais sorodiscordantes enfrentam vários problemas não enfrentados pelos casais soroconcordantes, incluindo decisões sobre qual nível de atividade sexual é confortável para eles, sabendo que praticar sexo seguro reduz, mas não elimina, o risco de transmissão ao parceiro HIV-negativo. Pesquisas envolvendo casais sorodiferentes ofereceram percepções sobre como o vírus é transmitido e como os indivíduos HIV positivos podem reduzir (pt)
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