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Satralizumab, sold under the brand name Enspryng, is a humanized monoclonal antibody medication that is used for the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune disease. The drug is being developed by Chugai Pharmaceutical, a subsidiary of Roche. The most common side effects include the common cold (nasopharyngitis), headache, upper respiratory tract infection, inflammation of the lining of the stomach, rash, joint pain, extremity pain, fatigue and nausea. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication.

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rdf:type
rdfs:label
  • Satralizumab (de)
  • Satralizumab (en)
rdfs:comment
  • Satralizumab (Handelsname: Enspryng) ist ein Arzneistoff, der zur Behandlung von Neuromyelitis-optica-Spektrum-Erkrankungen (NMOSD) zugelassen ist. Der humanisierte monoklonaler Antikörper bindet an den Rezeptor von Interleukin-6 und blockiert dadurch die von diesem Zytokin vermittelten Entzündungsprozesse und verlängert damit den Zeitraum zwischen Erkrankungsschüben. (de)
  • Satralizumab, sold under the brand name Enspryng, is a humanized monoclonal antibody medication that is used for the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune disease. The drug is being developed by Chugai Pharmaceutical, a subsidiary of Roche. The most common side effects include the common cold (nasopharyngitis), headache, upper respiratory tract infection, inflammation of the lining of the stomach, rash, joint pain, extremity pain, fatigue and nausea. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. (en)
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Link from a Wikipage to an external page
sameAs
dbp:wikiPageUsesTemplate
ATC suffix
  • AC19 (en)
ATC prefix
  • L04 (en)
c
CAS number
DrugBank
  • DB15762 (en)
H
KEGG
  • D11079 (en)
legal status
  • Rx-only (en)
legal US
  • Rx-only (en)
n
O
routes of administration
s
source
  • zu/o (en)
synonyms
  • SA-237, sapelizumab, satralizumab-mwge (en)
target
tradename
  • Enspryng (en)
type
  • mab (en)
UNII
  • YB18NF020M (en)
has abstract
  • Satralizumab (Handelsname: Enspryng) ist ein Arzneistoff, der zur Behandlung von Neuromyelitis-optica-Spektrum-Erkrankungen (NMOSD) zugelassen ist. Der humanisierte monoklonaler Antikörper bindet an den Rezeptor von Interleukin-6 und blockiert dadurch die von diesem Zytokin vermittelten Entzündungsprozesse und verlängert damit den Zeitraum zwischen Erkrankungsschüben. (de)
  • Satralizumab, sold under the brand name Enspryng, is a humanized monoclonal antibody medication that is used for the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune disease. The drug is being developed by Chugai Pharmaceutical, a subsidiary of Roche. The most common side effects include the common cold (nasopharyngitis), headache, upper respiratory tract infection, inflammation of the lining of the stomach, rash, joint pain, extremity pain, fatigue and nausea. Satralizumab regulates inflammation by inhibiting the interleukin-6 (IL-6) receptor, a key mediator of the immune response. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. (en)
DailyMedID
  • Satralizumab (en)
legal AU
  • S4 (en)
legal CA
  • Rx-only / Schedule D (en)
licence CA
  • Satralizumab (en)
mab type
  • mab (en)
pregnancy AU
  • C (en)
prov:wasDerivedFrom
page length (characters) of wiki page
alternative name
  • Enspryng (en)
CAS number
  • 1535963-91-7
DrugBank
  • DB15762
FDA UNII code
  • YB18NF020M
KEGG
  • D11079
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