Séamus Prendergast (born 1 January 1980) is an Irish hurler who played as a centre-forward at senior level for the Waterford county team. Born in Ardmore, County Waterford, Prendergast first played competitive hurling in his youth. He first arrived on the inter-county scene as a member of various Waterford teams at underage levels. Prendergast joined the senior panel during the 2001 championship and subsequently became a regular member of the starting fifteen. He went on to win four Munster medals and one National Hurling League medal. Prendergast was an All-Ireland runner-up on one occasion.