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About: Ro 3-0419     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : dbo:ChemicalCompound, within Data Space : dbpedia.org associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceChemical compoundchemical compound New Facet based on Instances of this Class

Ro 3-0419 is a highly toxic organophosphate acetylcholinesterase inhibitor. It is the neutral analog of Ro 3-0422. Although Ro 3-0419 is less potent than Ro 3-0422, it does not have a positively charged nitrogen atom, resulting in its ability to cross the blood brain barrier to inhibit cholinesterases in the brain. The intravenous LD50 of Ro 3-0419 is 1 mg/kg in mice.