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In enzymology, a retinol isomerase (EC 5.2.1.7) is an enzyme that catalyzes the chemical reaction all-trans-retinol 11-cis-retinol Hence, this enzyme has one substrate, all-trans-retinol, and one product, . These enzymes are alternatively referred to as retinoid isomerases. This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is all-trans-retinol 11-cis-trans-isomerase. This enzyme is also called all-trans-retinol isomerase. This enzyme participates in retinol metabolism.

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  • レチノールイソメラーゼ (ja)
  • Retinol isomerase (en)
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  • レチノールイソメラーゼ(Retinol isomerase、EC 5.2.1.7)は、以下の化学反応を触媒する酵素である。 all-trans-レチノール 11-cis-レチノール 従って、この酵素の基質はall-trans-レチノールのみ、生成物は11-cis-レチノールのみである。 この酵素は、異性化酵素、特にシス‐トランスイソメラーゼに分類される。系統名は、all-trans-レチノール 11-cis-trans-イソメラーゼ(all-trans-retinol 11-cis-trans-isomerase)である。この酵素は、レチノールの代謝にかかわっている。 (ja)
  • In enzymology, a retinol isomerase (EC 5.2.1.7) is an enzyme that catalyzes the chemical reaction all-trans-retinol 11-cis-retinol Hence, this enzyme has one substrate, all-trans-retinol, and one product, . These enzymes are alternatively referred to as retinoid isomerases. This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is all-trans-retinol 11-cis-trans-isomerase. This enzyme is also called all-trans-retinol isomerase. This enzyme participates in retinol metabolism. (en)
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  • retinol isomerase (en)
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  • retinol isomerase (en)
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  • In enzymology, a retinol isomerase (EC 5.2.1.7) is an enzyme that catalyzes the chemical reaction all-trans-retinol 11-cis-retinol Hence, this enzyme has one substrate, all-trans-retinol, and one product, . These enzymes are alternatively referred to as retinoid isomerases. This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is all-trans-retinol 11-cis-trans-isomerase. This enzyme is also called all-trans-retinol isomerase. This enzyme participates in retinol metabolism. In vertebrates, RPE65 is the active retinol isomerase in the visual cycle. A lack of RPE65 function results in congenital blindness in children (specifically Leber congenital amaurosis). Emixustat, a partial inhibitor of RPE65, is currently in FDA clinical trials for the treatment of age-related macular degeneration. (en)
  • レチノールイソメラーゼ(Retinol isomerase、EC 5.2.1.7)は、以下の化学反応を触媒する酵素である。 all-trans-レチノール 11-cis-レチノール 従って、この酵素の基質はall-trans-レチノールのみ、生成物は11-cis-レチノールのみである。 この酵素は、異性化酵素、特にシス‐トランスイソメラーゼに分類される。系統名は、all-trans-レチノール 11-cis-trans-イソメラーゼ(all-trans-retinol 11-cis-trans-isomerase)である。この酵素は、レチノールの代謝にかかわっている。 (ja)
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  • 5.2.1.7
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