Polyaspartic acid (PASA) is a biodegradable, water-soluble polymerized amino acid. It is a biodegradable replacement for water softeners and related applications. In nature, PASA has been found in as fragments of larger proteins with length up to 50 amino acids, but as of 2004 had not been isolated as a pure homo polymeric material from any natural source. The first isolation of synthetic oligomeric sodium polyaspartate, obtained by thermal polycondensation of aspartic acid, was reported by Hugo Schiff in late 19th century. Later it was proposed that thermal polymerization process leads through polysuccinimide intermediate. Polyaspartic acid is produced industrially in both the acid form and as the sodium polyaspartate salt.
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