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Pipazetate (INN) (brand names Dipect, Lenopect, Selvigon, Theratuss, Toraxan), or pipazethate (USAN), is a pyridobenzthiazine cough suppressant, closely related to the phenothiazine class. It binds to the sigma-1 receptor with an IC50 value of 190 nM. It also has local anesthetic action, and in large doses can produce seizures. Side effects, which are infrequent, include nausea, vomiting, drowsiness, fatigue, rash, and tachycardia.

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  • Pipazetate (en)
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  • Pipazetate (INN) (brand names Dipect, Lenopect, Selvigon, Theratuss, Toraxan), or pipazethate (USAN), is a pyridobenzthiazine cough suppressant, closely related to the phenothiazine class. It binds to the sigma-1 receptor with an IC50 value of 190 nM. It also has local anesthetic action, and in large doses can produce seizures. Side effects, which are infrequent, include nausea, vomiting, drowsiness, fatigue, rash, and tachycardia. (en)
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ATC suffix
  • DB11 (en)
ATC prefix
  • R05 (en)
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  • DB08796 (en)
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IUPAC name
KEGG
  • D05484 (en)
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SMILES
  • O=CN3c4ccccc4 (en)
StdInChI
StdInChIKey
  • DTVJXCOMJLLMAK-UHFFFAOYSA-N (en)
synonyms
  • Pipazethate; D-254; LG-254; SKF-70230A; SQ-15874 (en)
tradename
  • Dipect, Lenopect, Selvignon, Selvigon, Theratuss, Toraxan (en)
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