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About: Pho4     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:ProteinMolecule, within Data Space : dbpedia.org associated with source document(s)

Type: ThingBiomoleculeBiomoleculeProteinyago:WikicatTranscriptionFactorsyago:Abstraction100002137yago:Beginning107290905yago:Cause107326557yago:Event100029378yago:Factor107327805yago:Happening107283608yago:Origin107323922yago:PsychologicalFeature100023100yago:YagoPermanentlyLocatedEntityproteinumbel-rc:ProteinMolecule New Facet based on Instances of this Class

Pho4 is a protein with a basic helix-loop-helix (bHLH) transcription factor. It is found in S. cerevisiae and other yeasts. It functions as a transcription factor to regulate phosphate responsive genes located in yeast cells. The Pho4 protein homodimer is able to do this by binding to DNA sequences containing the bHLH binding site 5'-CACGTG-3'. This sequence is found in the promoters of genes up-regulated in response to phosphate availability such as the PHO5 gene.