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About: Perzinfotel     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:DrugProduct, within Data Space : dbpedia.org associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugyago:Abstraction100002137yago:Acid114607521yago:Chemical114806838yago:Compound114818238yago:Material114580897yago:Matter100020827yago:Part113809207yago:PhysicalEntity100001930yago:Quinone115000973yago:Relation100031921drugyago:Substance100019613yago:WikicatPhosphonicAcidsyago:WikicatQuinonesumbel-rc:DrugProduct New Facet based on Instances of this Class

Perzinfotel (EAA-090) is a drug which acts as a potent NMDA antagonist. It has neuroprotective effects and has been investigated for the treatment of stroke, but lacks analgesic effects. Nevertheless, it shows a good safety profile compared to older drugs, although further development of this drug has been discontinued. Prodrugs were developed since the oral bioavailability of perzinfotel is only around 3-5%.