In enzymology, a peptidylglycine monooxygenase (EC 1.14.17.3) is an enzyme that catalyzes the chemical reaction peptidylglycine + ascorbate + O2 peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O The 3 substrates of this enzyme are , ascorbate, and O2, whereas its 3 products are , dehydroascorbate, and H2O.
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| - Peptidilglicina monoossigenasi (it)
- ペプチジルグリシンモノオキシゲナーゼ (ja)
- Peptidylglycine monooxygenase (en)
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| - La peptidilglicina monoossigenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: peptidilglicina + ascorbato + O2 ⇄ peptidil(2-idrossiglicina) + deidroascorbato + H2O L'enzima è una proteina contenente rame. Le peptidilglicine con un amminoacidico neutrale nella penultima posizione sono i migliori substrati per l'enzima. Il prodotto è instabile e dismuta a gliossilato, in una reazione catalizzata dalla (numero EC 4.3.2.5). Coinvolto nel passo finale nella biosintesi della α-melanotropina e dei peptidi attivi biologicamente correlati. (it)
- ペプチジルグリシンモノオキシゲナーゼ（peptidylglycine monooxygenase）は、次の化学反応を触媒する酸化還元酵素である。 ペプチジルグリシン + アスコルビン酸 + O2 ペプチジル(2-ヒドロキシグリシン) + デヒドロアスコルビン酸 + H2O この酵素の基質は、アスコルビン酸、O2で、生成物は、デヒドロアスコルビン酸とH2Oである。補因子として銅を用いる。 組織名はpeptidylglycine,ascorbate:oxygen oxidoreductase (2-hydroxylating)で、別名にpeptidylglycine 2-hydroxylase、peptidyl α-amidating enzyme、peptide-α-amide synthetase、synthase, peptide α-amide、peptide α-amidating enzyme、peptide α-amide synthase、peptidylglycine α-hydroxylase、peptidylglycine α-amidating monooxygenase、PAM-A、PAM-B、PAMがある。 (ja)
- In enzymology, a peptidylglycine monooxygenase (EC 1.14.17.3) is an enzyme that catalyzes the chemical reaction peptidylglycine + ascorbate + O2 peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O The 3 substrates of this enzyme are , ascorbate, and O2, whereas its 3 products are , dehydroascorbate, and H2O. (en)
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| - peptidylglycine monooxygenase (en)
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| - peptidylglycine monooxygenase (en)
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| - In enzymology, a peptidylglycine monooxygenase (EC 1.14.17.3) is an enzyme that catalyzes the chemical reaction peptidylglycine + ascorbate + O2 peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O The 3 substrates of this enzyme are , ascorbate, and O2, whereas its 3 products are , dehydroascorbate, and H2O. This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with reduced ascorbate as one donor, and incorporation of one atom of oxygen into the other donor. The systematic name of this enzyme class is peptidylglycine,ascorbate:oxygen oxidoreductase (2-hydroxylating). Other names in common use include 2-hydroxylase, alpha-amidating enzyme, peptide-alpha-amide synthetase, synthase, peptide alpha-amide, peptide alpha-amidating enzyme, peptide alpha-amide synthase, alpha-hydroxylase, alpha-amidating monooxygenase, PAM-A, PAM-B, and PAM. It employs one cofactor, copper. (en)
- La peptidilglicina monoossigenasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: peptidilglicina + ascorbato + O2 ⇄ peptidil(2-idrossiglicina) + deidroascorbato + H2O L'enzima è una proteina contenente rame. Le peptidilglicine con un amminoacidico neutrale nella penultima posizione sono i migliori substrati per l'enzima. Il prodotto è instabile e dismuta a gliossilato, in una reazione catalizzata dalla (numero EC 4.3.2.5). Coinvolto nel passo finale nella biosintesi della α-melanotropina e dei peptidi attivi biologicamente correlati. (it)
- ペプチジルグリシンモノオキシゲナーゼ（peptidylglycine monooxygenase）は、次の化学反応を触媒する酸化還元酵素である。 ペプチジルグリシン + アスコルビン酸 + O2 ペプチジル(2-ヒドロキシグリシン) + デヒドロアスコルビン酸 + H2O この酵素の基質は、アスコルビン酸、O2で、生成物は、デヒドロアスコルビン酸とH2Oである。補因子として銅を用いる。 組織名はpeptidylglycine,ascorbate:oxygen oxidoreductase (2-hydroxylating)で、別名にpeptidylglycine 2-hydroxylase、peptidyl α-amidating enzyme、peptide-α-amide synthetase、synthase, peptide α-amide、peptide α-amidating enzyme、peptide α-amide synthase、peptidylglycine α-hydroxylase、peptidylglycine α-amidating monooxygenase、PAM-A、PAM-B、PAMがある。 (ja)
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