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Pentraxins (PTX), also known as pentaxins, are an evolutionary conserved family of proteins characterised by containing a pentraxin protein domain. Proteins of the pentraxin family are involved in acute immunological responses. They are a class of pattern recognition receptors (PRRs). They are a superfamily of multifunctional conserved proteins, some of which are components of the humoral arm of innate immunity and behave as functional ancestors of antibodies (Abs). They are known as classical acute phase proteins (APP), known for over a century.

AttributesValues
rdf:type
rdfs:label
  • Pentraxine (de)
  • Πεντραξίνες (el)
  • Pentraxine (fr)
  • Pentrassine (it)
  • Pentraxins (en)
  • Pentraxinas (pt)
rdfs:comment
  • Οι πεντραξίνες (αγγλ. pentraxins) είναι λεκτίνες που υιοθετούν μια ασυνήθιστη τεταρτοταγή δομή, στην οποία πέντε πανομοιότυπες συνδυάζονται ώστε να σχηματίσουν ένα επίπεδο δακτύλιο με μια κεντρική οπή. Η C-αντιδρώσα πρωτεΐνη είναι μια πεντράξινη που λειτουργεί για να περιορίσει τη βλάβη των ιστών, την οξεία φλεγμνονή, και τις αυτοάνοσες αντιδράσεις. (el)
  • Pentraxine sind entweder Proteine der Immunabwehr oder zu diesen homologe Proteine. Unterschieden werden kurze und lange Pentraxine. Ihre Funktion ist sehr unterschiedlich. Gemeinsames Merkmal ist eine Zusammensetzung aus je 5 gleichen , die kurzen Pentraxine sind zueinander und zu den C-terminalen Proteinhälften der langen Pentraxine homolog. (de)
  • Les pentraxines (ou pentaxines) sont une famille de protéines dont la structure est constituée de cinq monomères en anneau. Parmi les représentants de cette famille, il y a la protéine C réactive, la pentraxine 2, et la pentraxine 3. (fr)
  • Pentraxins (PTX), also known as pentaxins, are an evolutionary conserved family of proteins characterised by containing a pentraxin protein domain. Proteins of the pentraxin family are involved in acute immunological responses. They are a class of pattern recognition receptors (PRRs). They are a superfamily of multifunctional conserved proteins, some of which are components of the humoral arm of innate immunity and behave as functional ancestors of antibodies (Abs). They are known as classical acute phase proteins (APP), known for over a century. (en)
  • Le Pentrassine (o pentassine, pentraxine, o pentaxine), sono una famiglia di proteine altamente conservate lungo la filogenesi, contenenti un dominio caratteristico e implicate nelle risposte infiammatorie di fase acuta. Di questa famiglia fanno parte alcune proteine di fase acuta come la Proteina C Reattiva. La pentrassina 3 (PTX3) aumenta significativamente nel corso di infezioni severe e i suoi livelli nel liquor aiutano a distinguere una meningite batterica da una non batterica. (it)
  • As pentraxinas, também conhecidas como pentaxinas, são uma família conservada evolutivamente de proteínas caracterizadas por um domínio proteico de pentraxina. As proteínas da família da pentraxina são envolvidas em respostas imune agudas. Elas são conhecidas como proteínas de fase aguda (APP) por mais de um século. (pt)
name
  • Pentaxin family (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/CRP_pretty.png
dct:subject
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Wikipage revision ID
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dbp:wikiPageUsesTemplate
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PROSITE
  • PDOC00261 (en)
SCOP
caption
  • CRP drawn from (en)
InterPro
  • IPR001759 (en)
Pfam
  • PF00354 (en)
symbol
  • Pentaxin (en)
has abstract
  • Οι πεντραξίνες (αγγλ. pentraxins) είναι λεκτίνες που υιοθετούν μια ασυνήθιστη τεταρτοταγή δομή, στην οποία πέντε πανομοιότυπες συνδυάζονται ώστε να σχηματίσουν ένα επίπεδο δακτύλιο με μια κεντρική οπή. Η C-αντιδρώσα πρωτεΐνη είναι μια πεντράξινη που λειτουργεί για να περιορίσει τη βλάβη των ιστών, την οξεία φλεγμνονή, και τις αυτοάνοσες αντιδράσεις. (el)
  • Pentraxine sind entweder Proteine der Immunabwehr oder zu diesen homologe Proteine. Unterschieden werden kurze und lange Pentraxine. Ihre Funktion ist sehr unterschiedlich. Gemeinsames Merkmal ist eine Zusammensetzung aus je 5 gleichen , die kurzen Pentraxine sind zueinander und zu den C-terminalen Proteinhälften der langen Pentraxine homolog. (de)
  • Les pentraxines (ou pentaxines) sont une famille de protéines dont la structure est constituée de cinq monomères en anneau. Parmi les représentants de cette famille, il y a la protéine C réactive, la pentraxine 2, et la pentraxine 3. (fr)
  • Pentraxins (PTX), also known as pentaxins, are an evolutionary conserved family of proteins characterised by containing a pentraxin protein domain. Proteins of the pentraxin family are involved in acute immunological responses. They are a class of pattern recognition receptors (PRRs). They are a superfamily of multifunctional conserved proteins, some of which are components of the humoral arm of innate immunity and behave as functional ancestors of antibodies (Abs). They are known as classical acute phase proteins (APP), known for over a century. (en)
  • Le Pentrassine (o pentassine, pentraxine, o pentaxine), sono una famiglia di proteine altamente conservate lungo la filogenesi, contenenti un dominio caratteristico e implicate nelle risposte infiammatorie di fase acuta. Di questa famiglia fanno parte alcune proteine di fase acuta come la Proteina C Reattiva. La pentrassina 3 (PTX3) aumenta significativamente nel corso di infezioni severe e i suoi livelli nel liquor aiutano a distinguere una meningite batterica da una non batterica. (it)
  • As pentraxinas, também conhecidas como pentaxinas, são uma família conservada evolutivamente de proteínas caracterizadas por um domínio proteico de pentraxina. As proteínas da família da pentraxina são envolvidas em respostas imune agudas. Elas são conhecidas como proteínas de fase aguda (APP) por mais de um século. (pt)
CDD
  • cd00152 (en)
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