About: Open flow microperfusion

Facets (new session)
Description
Metadata
Settings
- Rule:
- Inverse Functional Properties:
- "Same As":

About: Open flow microperfusion Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Thing, within Data Space : dbpedia.org associated with source document(s)
QRcode icon

http://dbpedia.org/describe/?url=http%3A%2F%2Fdbpedia.org%2Fresource%2FOpen_flow_microperfusion

Open flow microperfusion (OFM) is a sampling method for clinical and preclinical drug development studies and biomarker research. OFM is designed for continuous sampling of analytes from the interstitial fluid (ISF) of various tissues. It provides direct access to the ISF by insertion of a small, minimally invasive, membrane-free probe with macroscopic openings. Thus, the entire biochemical information of the ISF becomes accessible regardless of the analyte's molecular size, protein-binding property or lipophilicity.

Attributes	Values
rdfs:label	Offene Mikroperfusion (de) Open flow microperfusion (en)
rdfs:comment	Die Offene Mikroperfusion (OFM) ist eine Methode zur Probenentnahme, die in klinischen und präklinischen Studien zur Arzneimittelentwicklung und Erforschung von Biomarkern Anwendung findet. OFM ist für die kontinuierliche Probenentnahme von Analyten aus der interstitiellen Flüssigkeit (ISF) verschiedener Gewebe konzipiert. Sie bietet direkten Zugang zur ISF durch Implantation eines kleinen, minimal invasiven, membranlosen Katheters mit makroskopischen Öffnungen. Dadurch wird die gesamte biochemische Information der ISF, unabhängig von der Molekülgröße, den Proteinbindungseigenschaften oder der Lipophilie der Analyten zugänglich. (de) Open flow microperfusion (OFM) is a sampling method for clinical and preclinical drug development studies and biomarker research. OFM is designed for continuous sampling of analytes from the interstitial fluid (ISF) of various tissues. It provides direct access to the ISF by insertion of a small, minimally invasive, membrane-free probe with macroscopic openings. Thus, the entire biochemical information of the ISF becomes accessible regardless of the analyte's molecular size, protein-binding property or lipophilicity. (en)
foaf:depiction
dcterms:subject	Cell biology Health research Membrane technology Clinical research Pharmacy Pharmacodynamics Drug discovery Medical research Biochemistry methods Life sciences industry Pharmaceutical industry Pharmacokinetics Food and Drug Administration Medical devices Catheters
Wikipage page ID	66518057 (xsd:integer)
Wikipage revision ID	1124399511 (xsd:integer)
Link from a Wikipage to another Wikipage	Potassium Muscle Nanoparticle Metabolite Peptide Cytokine Vesicle (biology and chemistry) In vivo Neurotransmitter Cell biology Health research Membrane technology Enzyme Glucose Brain Antibody Leptin Helmut List Pharmacodynamics Microdialysis Clinical research Pharmacy Pharmacodynamics Lipid metabolism Lipophilicity Nutrient Adipose tissue Albumin Drug discovery Food and Drug Administration Protein Medical research Interstitial fluid Biochemistry methods Life sciences industry Pharmaceutical industry Pharmacokinetics Food and Drug Administration Medical devices Lactic acid Bioavailability Bioequivalence Biomarker Blood–brain barrier Catheters Sodium Injury Insulin Obesity Neuroactive Chemical messenger (disambiguation) Pharmacokinetics Ex vivo Nanocarriers Dermal tissue
Link from a Wikipage to an external page	https://www.joanneum.at/en/health
sameAs	Open flow microperfusion Open flow microperfusion Open flow microperfusion
thumbnail	wiki-commons:Special:FilePath/217_HTH_OFM_graphic_v5w.png?width=300
has abstract	Die Offene Mikroperfusion (OFM) ist eine Methode zur Probenentnahme, die in klinischen und präklinischen Studien zur Arzneimittelentwicklung und Erforschung von Biomarkern Anwendung findet. OFM ist für die kontinuierliche Probenentnahme von Analyten aus der interstitiellen Flüssigkeit (ISF) verschiedener Gewebe konzipiert. Sie bietet direkten Zugang zur ISF durch Implantation eines kleinen, minimal invasiven, membranlosen Katheters mit makroskopischen Öffnungen. Dadurch wird die gesamte biochemische Information der ISF, unabhängig von der Molekülgröße, den Proteinbindungseigenschaften oder der Lipophilie der Analyten zugänglich. OFM ist in der Lage, lipophile und hydrophile Substanzen, proteingebundene und ungebundene Wirkstoffe, Neurotransmitter, Peptide und Proteine, Antikörper, Nanopartikel und Nanoträger, Enzyme und Vesikel zu entnehmen. (de) Open flow microperfusion (OFM) is a sampling method for clinical and preclinical drug development studies and biomarker research. OFM is designed for continuous sampling of analytes from the interstitial fluid (ISF) of various tissues. It provides direct access to the ISF by insertion of a small, minimally invasive, membrane-free probe with macroscopic openings. Thus, the entire biochemical information of the ISF becomes accessible regardless of the analyte's molecular size, protein-binding property or lipophilicity. OFM is capable of sampling lipophilic and hydrophilic compounds, protein bound and unbound drugs, neurotransmitters, peptides and proteins, antibodies, nanoparticles and nanocarriers, enzymes and vesicles. (en)
prov:wasDerivedFrom	wikipedia-en:Open_flow_microperfusion?oldid=1124399511&ns=0
page length (characters) of wiki page	28282 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Open_flow_microperfusion
is Link from a Wikipage to another Wikipage of	OFM Microdialysis Open Flow Microperfusion
is Wikipage redirect of	Open Flow Microperfusion

Faceted Search & Find service v1.17_git139 as of Feb 29 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 08.03.3330 as of Mar 19 2024, on Linux (x86_64-generic-linux-glibc212), Single-Server Edition (62 GB total memory, 54 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software