About: Nucleoside-diphosphate kinase

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Nucleoside-diphosphate kinases (NDPKs, also NDP kinase, (poly)nucleotide kinases and nucleoside diphosphokinases) are enzymes that catalyze the exchange of terminal phosphate between different nucleoside diphosphates (NDP) and triphosphates (NTP) in a reversible manner to produce nucleotide triphosphates. Many NDP serve as acceptor while NTP are donors of phosphate group. The general reaction via ping-pong mechanism is as follows: XDP + YTP ←→ XTP + YDP (X and Y each represent different nitrogenous base). NDPK activities maintain an equilibrium between the concentrations of different nucleoside triphosphates such as, for example, when guanosine triphosphate (GTP) produced in the citric acid (Krebs) cycle is converted to adenosine triphosphate (ATP). Other activities include cell proliferat

Attributes	Values
rdf:type	Thing Biomolecule Biomolecule Enzyme yago:Abstraction100002137 yago:Activator114723079 yago:Catalyst114723628 yago:Chemical114806838 yago:Compound114818238 yago:Enzyme114732946 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 enzyme yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatEnzymes
rdfs:label	Nucléoside diphosphate kinase (fr) Nucleoside-diphosphate kinase (en) Nukleosiddifosfatkinas (sv)
rdfs:comment	Une nucléoside diphosphate kinase (NDK, aussi NDPK) est une phosphotransférase qui catalyse la réaction : ATP + nucléoside diphosphate ADP + nucléoside triphosphate. Ces enzymes catalysent l'échange d'un groupe phosphate entre différents nucléosides diphosphates. Comme le cycle de Krebs ne produit que de l'ATP, la nucléotide diphosphate kinase permet de maintenir un équilibre entre les concentrations des différents nucléosides triphosphates. (fr) Nukleosiddifosfatkinas är ett enzym som katalyserar överföringen av en fosfatgrupp från guanosintrifosfat (GTP) till adenosindifosfat (ADP), vilket genererar adenosintrifosfat (ATP). Detta är ett sätt att omvandla det GTP som bildas i citronsyracykeln till ATP. Nettoreaktion: GTP + ADP → GDP + ATP (sv) Nucleoside-diphosphate kinases (NDPKs, also NDP kinase, (poly)nucleotide kinases and nucleoside diphosphokinases) are enzymes that catalyze the exchange of terminal phosphate between different nucleoside diphosphates (NDP) and triphosphates (NTP) in a reversible manner to produce nucleotide triphosphates. Many NDP serve as acceptor while NTP are donors of phosphate group. The general reaction via ping-pong mechanism is as follows: XDP + YTP ←→ XTP + YDP (X and Y each represent different nitrogenous base). NDPK activities maintain an equilibrium between the concentrations of different nucleoside triphosphates such as, for example, when guanosine triphosphate (GTP) produced in the citric acid (Krebs) cycle is converted to adenosine triphosphate (ATP). Other activities include cell proliferat (en)
foaf:name	Nucleoside-diphosphate kinase (en)
name	Nucleoside-diphosphate kinase (en)
foaf:depiction
dcterms:subject	EC 2.7.4 Enzymes
Wikipage page ID	2281317 (xsd:integer)
Wikipage revision ID	1057400098 (xsd:integer)
Link from a Wikipage to another Wikipage	Catalyst Prokaryotes Pyrimidine Endocytosis Epithelial–mesenchymal transition Nucleotide Uridine triphosphate Cardiovascular G protein–coupled receptor Nucleoside EC 2.7.4 Enzymes Melanoma Gene expression Transfer RNA Proteolysis Citric acid cycle Enzyme Mitochondria Deoxyribonucleotide dbr:Thymidylate_synthase Bacteria Thymidine kinase Thymidylate kinase G protein Adenosine triphosphate dbr:Cyclic_adenosine_monophosphate Cytidine triphosphate Escherichia coli Nucleotides Guanosine pentaphosphate Guanosine triphosphate Histidine Histidine kinase Bacillus subtilis AMP-activated protein kinase Homology (biology) Homotetramer Signal transduction Myxococcus xanthus Ping-pong mechanism Thymidine kinase in clinical chemistry Metastasis Neuroblastoma Immunohistochemistry Ribosome Lipid synthesis Motor protein Oncogene Nucleoside triphosphate Polysaccharide Phosphorylation Tetramer Salmonella typhimurium Paralogous genes Caveola Gram negative Nucleoside monophosphate

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