New York State Route 39 (NY 39) was a 32.85-mile-long (52.87 km) state highway in the Hudson Valley region of New York in the United States. It stretched from NY 21 (now U.S. Route 44) in the town of Poughkeepsie to NY 22 in Patterson, New York. NY 39 was designated in the mid-1920s and was replaced with NY 202, NY 311, and part of NY 52 in the 1930 renumbering of state highways in New York.