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About: dbr:Neutrophil_elastase     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:WikicatEnzymes, within Data Space : dbpedia.org associated with source document(s)

Type: ThingBiomoleculegeneBiomoleculeGeneyago:Abstraction100002137yago:Activator114723079yago:Catalyst114723628yago:Chemical114806838yago:Compound114818238yago:Enzyme114732946yago:Macromolecule114944888yago:Material114580897yago:Matter100020827yago:Molecule114682133yago:OrganicCompound114727670yago:Part113809207yago:PhysicalEntity100001930yago:Protein114728724yago:Relation100031921HumanGeneyago:Substance100019613yago:Thing100002452yago:Unit109465459yago:WikicatEnzymes New Facet based on Instances of this Class

Neutrophil elastase (EC 3.4.21.37, leukocyte elastase, ELANE, ELA2, elastase 2, neutrophil, elaszym, serine elastase, subtype human leukocyte elastase (HLE)) is a serine proteinase in the same family as chymotrypsin and has broad substrate specificity. Neutrophil elastase is secreted by neutrophils during inflammation, and destroys bacteria and host tissue. It also localizes to neutrophil extracellular traps (NETs), via its high affinity for DNA, an unusual property for serine proteases.