About: Neuronal self-avoidance

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Neuronal self-avoidance, or isoneural avoidance, is an important property of neurons which consists in the tendency of branches (dendrites and axons) arising from a single soma (also called isoneuronal or sister branches) to turn away from one another. The arrangements of branches within neuronal arbors are established during development and result in minimal crossing or overlap as they spread over a territory, resulting in the typical fasciculated morphology of neurons (Fig 1).

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rdf:type	building
rdfs:label	Neuronal self-avoidance (en)
rdfs:comment	Neuronal self-avoidance, or isoneural avoidance, is an important property of neurons which consists in the tendency of branches (dendrites and axons) arising from a single soma (also called isoneuronal or sister branches) to turn away from one another. The arrangements of branches within neuronal arbors are established during development and result in minimal crossing or overlap as they spread over a territory, resulting in the typical fasciculated morphology of neurons (Fig 1). (en)
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dcterms:subject	Cell biology Animal developmental biology
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Wikipage revision ID	1121906721 (xsd:integer)
Link from a Wikipage to another Wikipage	Cadherin Rohon-Beard cell Mutation Retina DSCAM Inner plexiform layer Ligand binding assay Protein isoform Synaptogenesis Cell biology Gene trapping Genetic analysis Neuron RNA splicing Epidermis (skin) List of goldfish varieties Dendrite Zebrafish Peripheral nervous system Starburst amacrine cell Synapse Protocadherin Ganglion Alternative splicing Dirichlet distribution Knockout Neural development Retinal ganglion cell Animal developmental biology Cre-Lox recombination CDNA Synapses Ectodomain Ectopic expression Homologous recombination Neuronal tiling Arthropod eye Axon Axon guidance Somatosensory system Filopodia Growth cone Purkinje cells Immunoglobulin Carnegie stages Xenopus laevis Soma (biology) Trigeminal nerve Neurite Adult neurogenesis Exon In situ hybridization Mushroom bodies Pioneer neuron Integrins Role of cell adhesions in neural development Trigeminal ganglion Retina amacrine cell Amacrine cells dbr:Neuronal_communication
sameAs	Neuronal self-avoidance Neuronal self-avoidance Neuronal self-avoidance Neuronal self-avoidance
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has abstract	Neuronal self-avoidance, or isoneural avoidance, is an important property of neurons which consists in the tendency of branches (dendrites and axons) arising from a single soma (also called isoneuronal or sister branches) to turn away from one another. The arrangements of branches within neuronal arbors are established during development and result in minimal crossing or overlap as they spread over a territory, resulting in the typical fasciculated morphology of neurons (Fig 1). In opposition, branches from different neurons can overlap freely with one another. This propriety demands that neurons are able to discriminate "self", which they avoid, from "non-self" branches, with which they coexist. This neuronal self-recognition is attained through families of cell recognition molecules which work as individual barcodes, allowing the discrimination of any other nearby branch as either "self" or "non-self". Self-avoidance ensures that dendritic territories are covered completely and yet non-redundantly guaranteeing that branches achieve functionally appropriate coverage of input or output territories. requires the coordinated assembly of axons, dendrites, and synapses. Therefore, self-avoidance is necessary for proper neuronal wiring and postnatal development and, together with neuronal tiling (heteroneuronal avoidance), is a crucial spacing mechanism for patterning neural circuits that results in complete and nonredundant innervation of sensory or synaptic space. (en)
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is Link from a Wikipage to another Wikipage of	DSCAM Isoneural avoidance Protocadherin Neuronal tiling PCDH11X
is Wikipage redirect of	Isoneural avoidance
is foaf:primaryTopic of	wikipedia-en:Neuronal_self-avoidance

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