Mustafa Ruhi Efendi (1800 - 1893, Istanbul, Ottoman Empire) was a shaikh of the Naqshbandi tariqah and political leader in the Balkans during the Ottoman period. Born on the Aegean island Imbros (present-day Gökçeada in Turkey), he moved as a young man at the Vilayet of Kosovo to the city of Kalkandelen (present-day Tetovo in North Macedonia). He was one of the participants of the League of Prizren which established the basis of Albanian nationalism, and was elected "President of the Central Committee of the League".He was buried in the courtyard of the Yahya Efendi mausoleum in the Yıldız Palace park in Istanbul.