The muaythai tournaments at the 2022 World Games in Birmingham, Alabama, United States were held from 15 to 17 July 2022 at the Boutwell Memorial Auditorium. Originally scheduled to take place in 2021, the Games were rescheduled for July 2022 as a result of the 2020 Summer Olympics postponement due to the COVID-19 pandemic. It was the second time of muaythai including in the World Games.