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Membrane vesicle trafficking in eukaryotic animal cells involves movement of biochemical signal molecules from synthesis-and-packaging locations in the Golgi body to specific release locations on the inside of the plasma membrane of the secretory cell. It takes place in the form of Golgi membrane-bound micro-sized vesicles, termed membrane vesicles (MVs).

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  • Membrane vesicle trafficking (en)
  • 膜囊泡運輸 (zh)
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  • 真核動物細胞中的膜囊泡運輸（Membrane vesicle trafficking）涉及到重要的生化信號分子，從高爾基體的合成和包裝位置，向分泌細胞（Secretory cells）質膜內部特定的釋放位置移動，其形式為高爾基膜結合微型囊泡（Golgi membrane-bound micro-sized vesicles），亦可被稱為膜囊泡（MVs）。在此過程中，經「包裝」的細胞產物通過其質膜釋放或分泌到細胞外。然而，該囊泡膜會被分泌細胞所保留並循環使用。這在突觸、內分泌腺分泌、黏液分泌、嗜中性顆粒白血球分泌顆粒狀產物等方面均起著關鍵作用。發現這個現象的科學家被授予2013年度的諾貝爾獎。 在原核革蘭氏陰性菌細胞中，膜囊泡轉運是通過細菌外膜結合的納米大小囊泡（即細菌外膜囊泡、OMV）介導的。然而在這種情況下，OMV膜也被分泌出來，同時OMV內的物質也被分泌到細菌的外部。這種現象在宿主與病原體的相互作用、患者的內毒素休克、動植物的入侵和感染、種間細菌競爭、群體感應及胞吐作用等方面起著關鍵作用。 (zh)
  • Membrane vesicle trafficking in eukaryotic animal cells involves movement of biochemical signal molecules from synthesis-and-packaging locations in the Golgi body to specific release locations on the inside of the plasma membrane of the secretory cell. It takes place in the form of Golgi membrane-bound micro-sized vesicles, termed membrane vesicles (MVs). (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/Outer_membrane_vesicle_secretion_from_gram-negative_microbes_-_mechanism_proposed_(Original_work_of_R_C_YashRoy).png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Vesicle_Budding,_Motility_and_Fusion.jpg
  • http://commons.wikimedia.org/wiki/Special:FilePath/OMV-macrophage99.jpg
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  • Membrane vesicle trafficking in eukaryotic animal cells involves movement of biochemical signal molecules from synthesis-and-packaging locations in the Golgi body to specific release locations on the inside of the plasma membrane of the secretory cell. It takes place in the form of Golgi membrane-bound micro-sized vesicles, termed membrane vesicles (MVs). In this process, the packed cellular products are released or secreted outside the cell, across its plasma membrane. On the other hand, the vesicular membrane is retained and recycled by the secretory cells. This phenomenon has a major role in synaptic neurotransmission, endocrine secretion, mucous secretion, granular-product secretion by neutrophils, and other phenomena. The scientists behind this discovery were awarded Nobel prize for the year 2013. In prokaryotic, gram-negative bacterial cells, membrane vesicle trafficking is mediated through bacterial outer membrane bounded nano-sized vesicles, called bacterial outer membrane vesicles (OMVs). In this case, however, the OMV membrane is secreted as well, along with OMV-contents to outside the secretion-active bacterium. This different phenomenon has a major role in host-pathogen interactions, endotoxic shock in patients, invasion and infection of animals or plants, inter-species bacterial competition, quorum sensing, exocytosis, and other areas. (en)
  • 真核動物細胞中的膜囊泡運輸（Membrane vesicle trafficking）涉及到重要的生化信號分子，從高爾基體的合成和包裝位置，向分泌細胞（Secretory cells）質膜內部特定的釋放位置移動，其形式為高爾基膜結合微型囊泡（Golgi membrane-bound micro-sized vesicles），亦可被稱為膜囊泡（MVs）。在此過程中，經「包裝」的細胞產物通過其質膜釋放或分泌到細胞外。然而，該囊泡膜會被分泌細胞所保留並循環使用。這在突觸、內分泌腺分泌、黏液分泌、嗜中性顆粒白血球分泌顆粒狀產物等方面均起著關鍵作用。發現這個現象的科學家被授予2013年度的諾貝爾獎。 在原核革蘭氏陰性菌細胞中，膜囊泡轉運是通過細菌外膜結合的納米大小囊泡（即細菌外膜囊泡、OMV）介導的。然而在這種情況下，OMV膜也被分泌出來，同時OMV內的物質也被分泌到細菌的外部。這種現象在宿主與病原體的相互作用、患者的內毒素休克、動植物的入侵和感染、種間細菌競爭、群體感應及胞吐作用等方面起著關鍵作用。 (zh)
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