Manchester Exchange was a railway station in Salford, England, immediately north of Manchester city centre, which served the city between 1884 and 1969. The main approach road ran from the end of Deansgate, near Manchester Cathedral, passing over the River Irwell, the Manchester-Salford boundary and Chapel Street; a second approach road led up from Blackfriars Road. Most of the station was in Salford, with only the 1929 extension to platform 3 east of the Irwell in Manchester.