Leonard Ames Farmhouse is a historic home located at Mexico in Oswego County, New York. It is a large, Federal-style residence. The first section is a small 1+1⁄2-story structure built about 1815. It was enlarged by the addition of a large 2-story stone residence and with a 1+1⁄2-story wing built in 1835. It was listed on the National Register of Historic Places in 1991.