Lacson Avenue is the principal northwest–southeast artery located in Sampaloc district in northern Manila, Philippines. It is a 6-8 lane median divided avenue that runs approximately 2.9 kilometers (1.8 mi) from Tayuman Street in Santa Cruz to Nagtahan Interchange. It is a component of Circumferential Road 2 of the Manila arterial road network and N140 of the Philippine highway network.