About: Knee cartilage replacement therapy

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Articular cartilage, most notably that which is found in the knee joint, is generally characterized by very low friction, high wear resistance, and poor regenerative qualities. It is responsible for much of the compressive resistance and load bearing qualities of the knee joint and, without it, walking is painful to impossible. Osteoarthritis is a common condition of cartilage failure that can lead to limited range of motion, bone damage and invariably, pain. Due to a combination of acute stress and chronic fatigue, osteoarthritis directly manifests itself in a wearing away of the articular surface and, in extreme cases, bone can be exposed in the joint. Some additional examples of cartilage failure mechanisms include cellular matrix linkage rupture, chondrocyte protein synthesis inhibitio

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rdf:type	yago:Artifact100021939 yago:Corrective103111899 yago:Device103183080 yago:Implant103563710 yago:Instrumentality103575240 yago:Object100002684 yago:PhysicalEntity100001930 yago:Prosthesis104013729 yago:WikicatImplants yago:Whole100003553
rdfs:label	Knee cartilage replacement therapy (en)
rdfs:comment	Articular cartilage, most notably that which is found in the knee joint, is generally characterized by very low friction, high wear resistance, and poor regenerative qualities. It is responsible for much of the compressive resistance and load bearing qualities of the knee joint and, without it, walking is painful to impossible. Osteoarthritis is a common condition of cartilage failure that can lead to limited range of motion, bone damage and invariably, pain. Due to a combination of acute stress and chronic fatigue, osteoarthritis directly manifests itself in a wearing away of the articular surface and, in extreme cases, bone can be exposed in the joint. Some additional examples of cartilage failure mechanisms include cellular matrix linkage rupture, chondrocyte protein synthesis inhibitio (en)
name	Knee cartilage replacement therapy (en)
dcterms:subject	Knee treatments Orthopedic surgical procedures Implants (medicine)
Wikipage page ID	4984243 (xsd:integer)
Wikipage revision ID	1084466045 (xsd:integer)
Link from a Wikipage to another Wikipage	Meniscal cartilage replacement therapy Meniscus transplant Blood clot Knee treatments In vitro Chondrocytes Apoptosis Chondrocyte Chondrogenesis Autologous chondrocyte implantation Orthopedic surgical procedures Food and Drug Administration Osteoarthritis Microfracture surgery Transplant rejection Hyaline cartilage Implants (medicine) Collagen Medical treatment Articular cartilage damage Pig Sodium hyaluronate Cartilage Mesenchymal stem cell Immune system Mesenchymal stem cells Spheroids of human autologous matrix-associated chondrocytes Articular cartilage
Link from a Wikipage to an external page	http://orthoinfo.aaos.org
sameAs	Knee cartilage replacement therapy Knee cartilage replacement therapy Knee cartilage replacement therapy Knee cartilage replacement therapy
specialty	orthopedic (en)
dbp:wikiPageUsesTemplate	dbt:EMedicine dbt:Main_article dbt:Reflist dbt:Bone,_cartilage,_and_joint_procedures dbt:Infobox_medical_intervention
has abstract	Articular cartilage, most notably that which is found in the knee joint, is generally characterized by very low friction, high wear resistance, and poor regenerative qualities. It is responsible for much of the compressive resistance and load bearing qualities of the knee joint and, without it, walking is painful to impossible. Osteoarthritis is a common condition of cartilage failure that can lead to limited range of motion, bone damage and invariably, pain. Due to a combination of acute stress and chronic fatigue, osteoarthritis directly manifests itself in a wearing away of the articular surface and, in extreme cases, bone can be exposed in the joint. Some additional examples of cartilage failure mechanisms include cellular matrix linkage rupture, chondrocyte protein synthesis inhibition, and chondrocyte apoptosis. There are several different repair options available for cartilage damage or failure. "Maci" or autologous cultured chondrocytes on porcine collagen membrane, is a treatment to correct cartilage defects in the knee. This treatment has been approved by the Food and Drug Administration in 2016 for adult treatment only. (en)
prov:wasDerivedFrom	wikipedia-en:Knee_cartilage_replacement_therapy?oldid=1084466045&ns=0
page length (characters) of wiki page	12755 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Knee_cartilage_replacement_therapy
is rdfs:seeAlso of	Osteochondritis dissecans Autologous matrix-induced chondrogenesis
is Link from a Wikipage to another Wikipage of	Sanofi Meniscal cartilage replacement therapy Index of trauma and orthopaedics articles Autologous cultured chondrocytes on porcine collagen membrane Medical procedure Temperature-responsive polymer Articular cartilage stem cell paste grafting Cartilage Knee Knee Cartilage Replacement Therapy Spheroids of human autologous matrix-associated chondrocytes Cartilage Regeneration
is Wikipage redirect of	Knee Cartilage Replacement Therapy Cartilage Regeneration
is foaf:primaryTopic of	wikipedia-en:Knee_cartilage_replacement_therapy

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