Karen Kohanowich is a retired U.S. Naval officer and ocean research and technology program manager for the National Oceanic and Atmospheric Administration (NOAA)'s Office of Ocean Exploration and Research (OER). She was NOAA's Acting Director of the National Undersea Research Program (NURP) from 2006–2009, and served in various roles at OER, including Acting Deputy and Undersea Technology director, until retiring in 2018. In July 2006, she became an aquanaut on the NASA Extreme Environment Mission Operations 10 (NEEMO 10) crew.