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About: Junctional diversity     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Whole100003553, within Data Space : dbpedia.org associated with source document(s)

Type: yago:WikicatLymphocytesyago:BloodCell105449268yago:Cell100006484yago:FreePhagocyte105451265yago:Leukocyte105449959yago:LivingThing100004258yago:Lymphocyte105451384yago:Object100002684yago:Phagocyte105450888yago:PhysicalEntity100001930yago:SomaticCell105430628yago:Whole100003553 New Facet based on Instances of this Class

Junctional diversity describes the DNA sequence variations introduced by the improper joining of gene segments during the process of V(D)J recombination. This process of V(D)J recombination has vital roles for the vertebrate immune system, as it is able to generate a huge repertoire of different T-cell receptor (TCR) and immunoglobulin molecules required for pathogen antigen recognition by T-cells and B cells, respectively.