The John P. Parker House is a historic house museum at 300 North Front Street in Ripley, Ohio. It was home to former slave and inventor John P. Parker (1827–1900) from 1853 to his death in 1900. Parker was an abolitionist and a well-documented conductor on the Underground Railroad, helping hundreds of escaped slaves. The house was listed on the National Register of Historic Places in 1980, and it was further designated a National Historic Landmark in 1997. It is now owned and managed by a local nonprofit organization as a museum about Parker's life and the abolitionist movement.