Jimson Weed is an oil on linen painting by American artist Georgia O'Keeffe from 1936, located in the Indianapolis Museum of Art in Indianapolis, Indiana. It depicts four large blossoms of jimson weed. A similar work by O'Keeffe, Jimson Weed/White Flower No. 1, was sold by the Georgia O'Keeffe Museum at auction to Walmart heiress Alice Walton in 2014 for $44,405,000, more than tripling the previous world auction record for a piece by a female artist.