Ishkoshim District or Nohiya-i Ishkoshim (Russian: Ишкашимский район, Tajik: Ноҳияи Ишкошим) is a district in eastern Tajikistan, in the extreme south-west of the Gorno-Badakhshan Autonomous Region (GBAO). It borders Afghanistan along the river Panj to the south and to the west. The population of Ishkoshim district is 32,900 (1 January 2020 estimate).