The Isaac W. Dyer Estate is a historic property at 180 Fort Hill Road in Gorham, Maine. The property consists of an 1850s Greek Revival house, and a collection of farm-related outbuildings and landscaping added in the early 20th century as part of a transformation of the property into gentleman's farm by Isaac Watson Dyer, a prominent Portland lawyer. The property was listed on the National Register of Historic Places in 1998.