Irene M. Zoppi Rodríguez (née Miller Rodríguez; born August 22, 1966), is a U.S. Army officer and academic. She is the first Puerto Rican woman to attain the rank of general in the U.S. Army Reserve. Since February 2019, she has served as a deputy commanding general for United States Army South, as the director of the Army Reserve Engagement Cell for Individual Mobilization Augmentees. Zoppi is an adjunct professor at Strayer University. She has worked as an instructor for the National Intelligence University where she directed the university's academic center within the National Security Agency.