Interstate 49 (I-49) is an Interstate Highway in the state of Arkansas. There are two main sections of the highway across different sides of the state. The southern section starts at the Louisiana state line, then runs to Texarkana, at the Texas state line. The northern section begins at I-40 and at U.S. Highway 71 (US 71) in Alma and runs north to the Missouri state line, where the freeway continues into Missouri.