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The International Prognostic Scoring System (IPSS), published in 1997, is used by many doctors to help assess the severity of a patient's myelodysplastic syndrome (MDS). Based on the IPSS score, the patient's history, and his/her personal observations, the physician will design a treatment plan to address the MDS. The IPSS uses three "prognostic indicators" to develop a "score" which may be useful in understanding how the MDS may progress: Each indicator is rated according to its severity and the ratings are combined into a "score." Scores are sorted into one of four risk categories:

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  • International Prognostic Scoring System
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  • The International Prognostic Scoring System (IPSS), published in 1997, is used by many doctors to help assess the severity of a patient's myelodysplastic syndrome (MDS). Based on the IPSS score, the patient's history, and his/her personal observations, the physician will design a treatment plan to address the MDS. The IPSS uses three "prognostic indicators" to develop a "score" which may be useful in understanding how the MDS may progress: Each indicator is rated according to its severity and the ratings are combined into a "score." Scores are sorted into one of four risk categories:
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  • The International Prognostic Scoring System (IPSS), published in 1997, is used by many doctors to help assess the severity of a patient's myelodysplastic syndrome (MDS). Based on the IPSS score, the patient's history, and his/her personal observations, the physician will design a treatment plan to address the MDS. The IPSS uses three "prognostic indicators" to develop a "score" which may be useful in understanding how the MDS may progress: * the proportion of blast cells in the bonemarrow * the type of chromosomal changes, if any, in the marrow cells * the presence of one or more low blood cell counts (cytopenias) Each indicator is rated according to its severity and the ratings are combined into a "score." Scores are sorted into one of four risk categories: * low * intermediate-1 * intermediate-2 * high The two lower categories can be further described as the lower risk group while the two upper categories can be further described as the higher risk group. A revised IPSS, IPSS-R was published in 2012. IPSS-R is more refined in its prognostic precision and includes five instead of four prognostic groups.
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