About: Inclusion body myositis

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Inclusion body myositis (IBM) (/maɪoʊˈsaɪtɪs/) (sometimes called sporadic inclusion body myositis, sIBM) is the most common inflammatory muscle disease in older adults. The disease is characterized by slowly progressive weakness and wasting of both proximal muscles (located on or close to the torso) and distal muscles (close to hands or feet), most apparent in the finger flexors and knee extensors. IBM is often confused with an entirely different class of diseases, called hereditary inclusion body myopathies (hIBM). The "M" in hIBM is an abbreviation for "myopathy" while the "M" in IBM is for "myositis". In IBM, two processes appear to occur in the muscles in parallel, one autoimmune and the other degenerative. Inflammation is evident from the invasion of muscle fibers by immune cells. Deg

Attributes	Values
rdf:type	Thing Fuchs' dystrophy disease umbel-rc:AilmentCondition
rdfs:label	التهاب العضلات المشتمل (ar) Sporadische Einschlusskörpermyositis (de) Miositis por cuerpos de inclusión (es) Inclusion body myositis (en) Miosite da corpi inclusi (it) 封入体筋炎 (ja) 포함체 근육염 (ko) Wtrętowe zapalenie mięśni (pl) Miosite por corpúsculos de inclusão (pt) Inklusionskroppsmyosit (sv)
rdfs:comment	التهاب العضلات المشتمل أو اعتلال عضلي مشتمل(بالإنجليزية: Inclusion body myositis)‏ هو مرض عضلي يتميز بالتسبب في ضعف وويتددرج ببطءفي العضلات ويصيبها بالهزال . (ar) Die sporadische Einschlusskörpermyositis (sporadic Inclusion Body Myositis; sIBM) zählt zu der Gruppe der entzündlichen Muskelerkrankungen (Idiopathische entzündliche Myopathie). Der Begriff „Inclusion Body Myositis“ wurde 1971 geprägt. Allerdings wurden bereits 1967 im Muskelgewebe eines Patienten mit Polymyositis IBM-ähnliche Veränderungen bei passender Klinik beschrieben. Neben der sporadischen Form (sIBM) findet sich auch eine hereditäre Variante (hIBM), bei der es sich um eine nicht-entzündliche Muskelerkrankung handelt. (de) Per miosite da corpi inclusi in campo medico, si intende una forma di miosite di tipo infiammatorio. (it) 포함체 근육염(包含體筋肉炎, inclusion body myositis, 봉입체 근염(封入體筋炎)은 먼쪽과 몸쪽 근육이 천천히 진행되는 약화 및 소모를 보이는 으로, 대개가 팔과 다리 근육에 나타난다. 두 가지 유형이 있다: 산발성 근육염(sIBM), (hIBM) 약화는 천천히 오며(수개월에서 1년), 진행도는 꾸준하며 일반적으로 팔과 다리 근육의 심각한 약화 및 소모로 이어진다. 여성 보다 남성에게 더 흔하다. 환자들은 을 수행하는 것이 불가능하며 대부분이 증상이 온지 5~10년 내에 보조 기구를 필요로 한다. sIBM은 심각한 질병으로 취급되지는 않으나 추락으로 인한 심각한 상해의 위험이 증가된다. 일반적이면서 잠재적으로 치명적인 합병증은 연하곤란이다. 이 질병에 대한 효과적인 치료법은 없다. (ko) 封入体筋炎（IBM: Inclusion body myositis）は、炎症性ミオパチーの3つの主要なグループのひとつ。50歳以上の炎症性ミオパチーにおいてはもっとも頻度の高いものである。 (ja) Miosite por corpúsculos de inclusão é uma doença inflamatória do músculo, caracterizada pela fraqueza muscular lentamente progressiva tanto distal como proximal, mais evidente na musculatura dos braços e pernas. (pt) Wtrętowe zapalenie mięśni (ang. (sporadic) Inclusion Body Myositis, w skrócie: (s)IBM) – wolno postępujące, zwyrodnieniowe zapalenie mięśni szkieletowych. Występuje zwykle po 50 roku życia i charakteryzuje się osłabieniem określonych grup mięśni oraz typowymi zmianami w obrazie histopatologicznym. Etiologia jest nieznana i nie ma skutecznego leczenia. (pl) Inklusionskroppsmyosit (engelska: inclusion body myositis, IBM) är en ovanlig sorts muskeldystrofi och muskelinflammation (myosit) vid vilken det sker en ansamling av bindväv och proteiner i muskelfibrerna, vilket leder till förtvining av muskler och muskelsvaghet. Orsaken till sjukdomen är okänd. (sv) Inclusion body myositis (IBM) (/maɪoʊˈsaɪtɪs/) (sometimes called sporadic inclusion body myositis, sIBM) is the most common inflammatory muscle disease in older adults. The disease is characterized by slowly progressive weakness and wasting of both proximal muscles (located on or close to the torso) and distal muscles (close to hands or feet), most apparent in the finger flexors and knee extensors. IBM is often confused with an entirely different class of diseases, called hereditary inclusion body myopathies (hIBM). The "M" in hIBM is an abbreviation for "myopathy" while the "M" in IBM is for "myositis". In IBM, two processes appear to occur in the muscles in parallel, one autoimmune and the other degenerative. Inflammation is evident from the invasion of muscle fibers by immune cells. Deg (en) La miositis por cuerpos de inclusión es una enfermedad poco frecuente que afecta a los músculos estriados y suele dar las primeras manifestaciones alrededor de los 50 años. Los síntomas consisten en debilidad y atrofia muscular que se manifiesta inicialmente en los cuádriceps y los músculos que flexionan los dedos de las manos, por lo que existe dificultad para realizar determinados movimientos, entre ellos levantarse de una silla y asir o levantar objetos. Progresivamente se afectan otros músculos, entre ellos los de la cara, y aparecen complicaciones como disfagia. No se saben las causas exactas del mal y tampoco se ha identificado ninguna mutación que lo origine. Cuando se observa una biopsia del músculo afectado al microscopio, se identifican fenómenos inflamatorios, por lo que la mios (es)
foaf:name	Inclusion body myositis (en)
name	Inclusion body myositis (en)
foaf:depiction
dcterms:subject	Inflammations Muscular disorders Systemic connective tissue disorders
Wikipage page ID	15538 (xsd:integer)
Wikipage revision ID	1122661342 (xsd:integer)
Link from a Wikipage to another Wikipage	Prednisone Quadriceps Electromyography Endoplasmic reticulum List of flexors of the human body Meta-analysis SQSTM1 Biceps Dermatomyositis Anti-inflammatory Antigen Deconditioning Dysphagia Inclusion bodies Inflammatory myopathy Inflammations Creatine kinase Amyloid Vacuole Leukemia Life expectancy Major histocompatibility complex Malnutrition Muscle atrophy Activities of daily living Tibialis anterior muscle Triceps Father Stu Beta amyloid Foot drop Respiration (physiology) Muscular disorders T cells Hereditary inclusion body myopathy Torso Systemic connective tissue disorders Aspiration pneumonia Polymyositis Human leukocyte antigen HTLV-1 Idiopathic Immunosuppressant Knee Becker's muscular dystrophy Valosin-containing protein Inflammatory myopathies Neurology Neuromuscular medicine Lymphocyte Exercise therapy for idiopathic inflammatory myopathies Finger NT5C1A Multisystem proteinopathy Reverse transcribing virus Rheumatology Symptomatic treatment Limb girdle muscular dystrophy Proteosome Flexor Immunomodulatory Extensor

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