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Imipenem/cilastatin, sold under the brand name Primaxin among others, is an antibiotic useful for the treatment of a number of bacterial infections. It is made from a combination of imipenem and cilastatin. Specifically it is used for pneumonia, sepsis, endocarditis, joint infections, intra-abdominal infections, and urinary tract infections. It is given by injection into a vein or muscle. Imipenem/cilastatin was first sold in 1987. It is on the World Health Organization's List of Essential Medicines.

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  • اميبينيم/سيلاستاتين (ar)
  • Imipenem/cilastatina (es)
  • Imipenem/cilastatin (en)
  • イミペネム・シラスタチン (ja)
  • Imipenem/cilastatina (pt)
  • Imipenem e cilastatina (pt)
  • 亚胺培南/西司他丁 (zh)
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  • الاميبينيم\سيلاستين هو مضاد حيوي يغطي العديد من فصائل البكتيريا و يعتبر من المضادات المقاومة للبيتا لاكتاميز وهو يحتوي على كميات متماثلة من الامبينيم والسيلاستين. و هو يصنف ضمن الكاربابينيم. (ar)
  • イミペネム・シラスタチン(Imipenem/cilastatin)は、商標名:チエナム(Primaxin)で販売されている、多数のの治療に使用される医薬品である。 (ja)
  • Imipenem é um antibiótico, do subgrupo do carbapenem, com o maior espectro dentre os betalactâmico e altamente resistente às betalactamases, o que o torna útil para infecçoes graves polimicrobianas e hospitalárias. Sempre vem combinado a cilastatina, um inibidor da enzima renal que inativa o imipenem, sem atividade antibacteriana. Descoberto em 1985, é derivado de um composto chamado que é produzido pela bactéria Streptomyces cattleya. Nome comercial: TIENAM ou PRIMAXINA, Injetável, 250 mg ou 500 mg. (pt)
  • Imipenem/cilastatina (nomes comerciais: Tienam, entre outros) é uma associação medicamentosa utilizada pela medicina como antibiótico. (pt)
  • 亚胺培南/西司他丁 (Imipenem/cilastatin),是一种用于治疗各类严重感染的复方抗生素制剂 。 它由亚胺培南和的组合制成,通过静脉注射或肌肉注射给药 。 临床应用其钠盐的形式,即亚胺培南西司他丁钠(默沙东上市商品名为Tienam)。该药常见的副作用包括恶心, 腹泻和注射部位的疼痛, 其他副作用包括伪膜性结肠炎和过敏反应(包括过敏性休克)。 亚胺培南属于碳青霉烯类药物,通过干扰细菌的细胞壁合成发挥药理作用 , 而西司他丁则通过阻断肾脱氢肽酶I的活性来提高亚胺培南的稳定性。 它被列于世界卫生组织基本药物清单,是卫生系统所需的最有效和最安全的药物之一。 (zh)
  • Imipenem/cilastatina, que se vende con el nombre comercial Primaxin entre otros, es un antibiótico útil para el tratamiento de varias infecciones bacterianas.​ Está hecho de una combinación de imipenem y cilastatina.​ Específicamente se usa para neumonía, sepsis, endocarditis, infecciones de articulaciones, infecciones intraabdominales e infecciones del tracto urinario.​ Se administra mediante inyección en una vena o músculo.​ (es)
  • Imipenem/cilastatin, sold under the brand name Primaxin among others, is an antibiotic useful for the treatment of a number of bacterial infections. It is made from a combination of imipenem and cilastatin. Specifically it is used for pneumonia, sepsis, endocarditis, joint infections, intra-abdominal infections, and urinary tract infections. It is given by injection into a vein or muscle. Imipenem/cilastatin was first sold in 1987. It is on the World Health Organization's List of Essential Medicines. (en)
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