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Idiopathic CD4+ lymphocytopenia (ICL) is a rare medical syndrome in which the body has too few CD4+ T lymphocytes, which are a kind of white blood cell. ICL is sometimes characterized as "HIV-negative AIDS", though, in fact, its clinical presentation differs somewhat from that seen with HIV/AIDS. People with ICL have a weakened immune system and are susceptible to opportunistic infections, although the rate of infections is lower than in people with AIDS.

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  • Idiopathic CD4+ lymphocytopenia (en)
  • Lymphocytopénie CD4 idiopathique (fr)
  • Linfocitopenia idiopatica delle cellule T CD4+ (it)
  • 原发性CD4+淋巴细胞减少症 (zh)
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  • Idiopathic CD4+ lymphocytopenia (ICL) is a rare medical syndrome in which the body has too few CD4+ T lymphocytes, which are a kind of white blood cell. ICL is sometimes characterized as "HIV-negative AIDS", though, in fact, its clinical presentation differs somewhat from that seen with HIV/AIDS. People with ICL have a weakened immune system and are susceptible to opportunistic infections, although the rate of infections is lower than in people with AIDS. (en)
  • La linfocitopenia idiopatica delle cellule T CD4+ (ICL) è una sindrome molto rara. In questa condizione, il corpo ha troppo pochi linfociti T CD4+, un tipo particolare di glubuli bianchi. A volte viene definito impropriamente "AIDS senza HIV" dai dissidenti sull'eziologia dell'AIDS, sebbene la presentazione clinica differisca da quella riscontrata nell'HIV/AIDS. (it)
  • 原发性 CD4+ 淋巴细胞减少症 (idiopathic CD4+ lymphocytopenia, ICL) 是一种极为罕见的综合徵。 发病时, 患者体内的 CD4+ T 淋巴细胞 (白细胞的一种) 数量过低。 这种疾病有时被 (AIDS denialists) 称作 “HIV-阴性 AIDS”, 但它的临床表现与 HIV/AIDS 的有所不同。 由於 ICL 患者的免疫系统变弱, 他们更易受到机会性感染, 但感染率比 AIDS 患者的低。 (zh)
  • On parle de lymphocytopénie CD4 idiopathique (ou ICL) lorsque les lymphocytes CD4+ tombent au-dessous de 300 par millimètre cube, ou qu'ils constituent moins de 20 % du total des lymphocytes, en l'absence d'infection due au VIH ou à d'autres causes connues d'immunodéficience. C'est un syndrome rare, hétérogène, et qui ne semble pas être provoqué par un agent transmissible. Ceux qui en sont atteints sont sensibles aux infections opportunistes, à savoir , mycobactérie atypique et pneumonie à Pneumocystis jiroveci (PCP). (fr)
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  • (en)
  • Idiopathic CD4+ lymphocytopenia (en)
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  • Idiopathic CD4+ lymphocytopenia (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/Autosomal_dominant_-_en.svg
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ICD
  • D72.8 (en)
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  • D018344 (en)
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  • Idiopathic CD4+ lymphocytopenia is inherited via autosomal dominant manner (en)
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  • Immunodeficiency 13 (en)
has abstract
  • Idiopathic CD4+ lymphocytopenia (ICL) is a rare medical syndrome in which the body has too few CD4+ T lymphocytes, which are a kind of white blood cell. ICL is sometimes characterized as "HIV-negative AIDS", though, in fact, its clinical presentation differs somewhat from that seen with HIV/AIDS. People with ICL have a weakened immune system and are susceptible to opportunistic infections, although the rate of infections is lower than in people with AIDS. (en)
  • On parle de lymphocytopénie CD4 idiopathique (ou ICL) lorsque les lymphocytes CD4+ tombent au-dessous de 300 par millimètre cube, ou qu'ils constituent moins de 20 % du total des lymphocytes, en l'absence d'infection due au VIH ou à d'autres causes connues d'immunodéficience. C'est un syndrome rare, hétérogène, et qui ne semble pas être provoqué par un agent transmissible. Ceux qui en sont atteints sont sensibles aux infections opportunistes, à savoir , mycobactérie atypique et pneumonie à Pneumocystis jiroveci (PCP). Les critères pour le diagnostic de lymphocytopénie CD4 idiopathique comprennent les signes suivants : * La cellule de CD4 mesurée au moins deux fois compte moins de 300/mm3 ou un pourcentage de CD4 inférieur à 20 sur le total des lymphocytes * Une infection au VIH n'a pu être prouvée en laboratoire * Absence d'une explication alternative de la lymphocytopénie CD4 L'ICL est une maladie rare : en 1993, un total de 47 cas vérifiés ont été cités dans une enquête financée par les Centers for Disease Control. À la différence de la chute du nombre de cellules CD4 provoquée par le VIH, les malades atteints de lymphocytopénie CD4 idiopathique ont généralement un pronostic favorable. (fr)
  • La linfocitopenia idiopatica delle cellule T CD4+ (ICL) è una sindrome molto rara. In questa condizione, il corpo ha troppo pochi linfociti T CD4+, un tipo particolare di glubuli bianchi. A volte viene definito impropriamente "AIDS senza HIV" dai dissidenti sull'eziologia dell'AIDS, sebbene la presentazione clinica differisca da quella riscontrata nell'HIV/AIDS. (it)
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